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Chimie moléculaire Paris Centre
ÉCOLE DOCTORALE 406

CulturChem, les séminaires de chimie moléculaire

L'ED organise un cycle de séminaire hebdomadaire CulturChem, chaque lundi à 11h sur le Campus Pierre et Marie Curie, couloir 54-55, salle 205, avec invitation de conférenciers extérieurs, nationaux comme internationaux.

Les professeurs invités dans le cadre des laboratoires et de l'ED proposent généralement aux doctorants une série de cours sur une thématique donnée.

Pour tous renseignements veuillez contacter : Dr Cyril Ollivier, UPMC, Tour 32 - 42, 5ème étage, case 229, 4 place Jussieu, 75005 PARIS

tél : 01 44 27 38 50 / fax : 01 44 27 73 60 e-mail : cyril.ollivier@upmc.fr

17/09/18

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Les séminaires CulturChem

    • Organic-, coordination-chemistry and theranostic: influence of the full control of the macrocycle design on the biological properties.

      Séminaire du Prof Raphaël Tripier (Université de Brest)
      Abstract :
       If the importance of azamacrocyclic chelates in imaging (MRI, PET, optical probes) and therapy (radiotherapy) is now well establish, the challenge to find good chelators able to be used in both diagnostic and therapeutic applications persists. Indeed, there is still no “ideal” ligand able to coordinate different metallic cations of...

    • Biomolecular Hydration Shells: Dynamics and Biochemical Role

      Séminaire du Dr Damien Laage (Department of Chemistry, Ecole Normale Supérieure, PSL-SU-CNRS)
      Abstract :
      The structure and function of biomolecules are strongly influenced by their hydration shells. Two key challenges are thus first to determine the extent to which the structural and dynamical properties of these shells differ from those of bulk water, and second to elucidate the role played by water...

    • Emerging 1D and 2D d10 Coinage Metal Organic Chalcogenolate Coordination Polymers for Optical Technologies

      Séminaire du Dr Aude Demessence (IRCELYON)
      Abstract :
      Hybrid materials with chalcogenate ligands (ER = SR, SeR, TeR) and d10 coinage metals (M(I) = Cu, Ag and Au) are known for a long time mainly in the domains of biology and pharmaceutics. Indeed, copper-thiolates are present in most of the living organisms as metalloproteins, silver-thiolates are recognized for their anti-bacterial activity and some...

    • Platforms for the generation and high-throughput screening of SICLOPPS cyclic peptide libraries.

      Séminaire du Prof Ali Tavassoli (University of Southampton)
      Abstract :
      Cyclic peptide libraries have demonstrated significant potential when employed against challenging targets such as protein– protein interactions. SICLOPPS is a method for the intracellular generation of cyclic peptide libraries of over a hundred million members. We have interfaced SICLOPPS libraries with a variety of cell-based...

    • Development of radical based synthetic strategies for the total synthesis of natural products and Posttranslational modification of proteins

      Séminaire du Prof Heeyon Lee (Korean Advanced Institute of Science & Technology)
      Abstract :
      Tandem cycloaddition reaction of allenyldiazao precursor vis via trimethylenemethane(TMM)-diyl was developed to contruct complex polycyclic structures in a single operation. This TMM-diyl cycloaddition reaction was successfully applied to the total synthesis of natural products with very challenging structural...

    • Engineering catalytic sites and molecular recognition in designed peptide scaffolds

      Séminaire du Dr Olga Iranzo (Institut des Sciences Moléculaires de Marseille - UMR CNRS 7313 Aix-Marseille Université)
      Abstract :
      Peptide-based frameworks constitute very attractive and versatile platforms for the development of novel systems with tailor-made properties and functionalities. They are chiral and have structural and chemical diversity (proteinogenic and non-proteinogenic amino acids),...

    • Heterocycles from the sea, a light from the abyss

      Séminaire du Dr Yves L. Janin (CNRS - Institut Pasteur)
      Abstract :
      A growing proportion of bioluminescent reporting systems are using imidazo[1,2-∝]pyrazine luciferins such as the natural product coelenterazine or the analog furimazine along with photoproteins or luciferases from sea creatures. Our contribution has led to an original (gram-scale) synthesis of this heterocyclic system, the preparation...

    • Bio-inspired peptide-like ligands to help understanding metal toxicity, regulation and detoxification

      Séminaire du Dr Pascale Delangle (CEA Grenoble, France)
      Abstract :
      Peptides are promising metal-chelating agents, which offer many advantages over synthetic chemical compounds for biological and medical applications. They are made of the same building blocks as proteins and are therefore excellent mimics of biological sites that help predicting high affinity metal binding environments in vivo. They...

    • Dearomatizations of Nitroarenes by additions and cycloadditions

      Séminaire du Dr Isabelle Chataigner (Université de Rouen Normandie)
      Abstract :
      . Involving arenes in dearomatizing addition and/or cycloaddition reactions is an attractive and convergent approach to construct complex polycycles from easily accessible substrates, however, challenging because of their intrinsic stability.
      Nitroarenes are interesting substrates in this context, allowing to carry out various...

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    Contact

    Directeur

    cyril.ollivier@sorbonne-universite.fr (cyril.ollivier @ upmc.fr)

     

    Directeur adjoint

     

     

    Secrétariat

    Irène Rasoarinoro (irene.rasoarinoro @ upmc.fr)

    Tel. : 01 44 27 38 48

     

    UPMC - ED 406

    Tour 32 - 42

    Bureau 114 (1er étage)

    BC 63 - 4 Place Jussieu 

    75252 Paris cedex 5